This improved model is compared with the classical model, which neglects these aberrations in the experimental setup.įinally, the advantage of the simultaneous regularization method over averaging over single-angle results is demonstrated. Therefore, for a given bimodal radii distribution and different scattering angles data were simulated taking into account the finite aperture of the detector as well as the laser light backscattered at the back of the cuvette. The described method works in a range of concentrations where the mesh size is comparable with the. The data analysis is performed combining theoretical descriptions of nonergodicity and semiflexible polymer dynamics. In the second part the sensitivity of the nonlinear simultaneous multi-angle regularization to aberrations in the experimental set-up is investigated. We show that the average mesh size of amyloid fibril gels can be extracted from simple dynamic light scattering experiments. On the other hand, with increasing number of photons the correlations of the errors of the autocorrelation time function become important: The non-diagonal elements of the covariance matrix of the data errors increase and may become of the order of the diagonal elements. The more the errors increase, however, the more important the error model becomes. Dynamic Light Scattering (DLS) is a technique classically used for measuring the size of particles typically in the sub-micron region, dispersed in a liquid. With decreasing measurement time the errors of the autocorrelation time function increase. In the first part of this paper, the influence of the correlation of the errors of the autocorrelation time function is considered. In the following three aspects of an improved data analysis are discussed for multi-angle dynamic light scattering. 1 In the scope of DLS, temporal fluctuations are usually analyzed using the intensity or photon auto-correlation function. DLS is based on the determination of the diffusion coefficient of particles freely moving in a fluid, a task that can be tackled by measuring the auto- or cross. Then the analysis of the data becomes a central point and it is worthwhile to accept some numerical efforts and an increased calculation time caused by more sophisticated data analysis. In dynamic light scattering the signal to noise ratio may become very low because of short measurement times or low intensities. This volume is directed in part to the philosophy and current practice in dynamic light scattering: single photon correlation techniques are introduced, a discussion of noise on photon correlation functions is given and data analysis in dynamic light scattering to polymer structure analysis is presented and a comprehensive introduction to diffusing wave spectroscopy is given.